Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50399695'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50399695 (CHEMBL2178933) Show SMILES Cc1nc(C)c(nc1C(N)=O)-c1ccc(cc1)[C@H]1CC[C@H](CCO)CC1 |r,wU:17.18,wD:20.22,(37.77,-23.43,;39.1,-22.65,;40.44,-23.43,;41.77,-22.65,;43.1,-23.42,;41.77,-21.12,;40.43,-20.35,;39.1,-21.11,;37.77,-20.34,;36.43,-21.11,;37.77,-18.8,;43.1,-20.35,;44.43,-21.12,;45.77,-20.35,;45.76,-18.8,;44.43,-18.04,;43.1,-18.81,;47.1,-18.03,;47.09,-16.49,;48.43,-15.72,;49.76,-16.49,;51.1,-15.72,;52.43,-16.49,;53.76,-15.72,;49.76,-18.03,;48.43,-18.8,)| Show InChI InChI=1S/C21H27N3O2/c1-13-19(24-20(21(22)26)14(2)23-13)18-9-7-17(8-10-18)16-5-3-15(4-6-16)11-12-25/h7-10,15-16,25H,3-6,11-12H2,1-2H3,(H2,22,26)/t15-,16-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillography				J Med Chem 55: 10610-29 (2012) Article DOI: 10.1021/jm301296t BindingDB Entry DOI: 10.7270/Q2XD12T3
					More data for this Ligand-Target Pair