Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50399698'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50399698 (CHEMBL2178930) Show SMILES CCc1nc(C)c(nc1-c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1)C(N)=O |r,wU:15.16,wD:18.20,(67.34,-12.09,;67.33,-10.55,;66,-9.78,;64.67,-10.55,;63.33,-9.78,;61.99,-10.55,;63.33,-8.24,;64.66,-7.47,;66,-8.25,;67.33,-7.48,;68.66,-8.25,;70,-7.48,;69.99,-5.93,;68.66,-5.16,;67.33,-5.93,;71.33,-5.16,;71.32,-3.62,;72.65,-2.85,;73.99,-3.62,;75.32,-2.85,;76.66,-3.62,;77.99,-2.85,;76.66,-5.16,;73.99,-5.16,;72.66,-5.93,;62,-7.47,;60.66,-8.24,;62,-5.93,)| Show InChI InChI=1S/C22H27N3O3/c1-3-18-21(25-20(22(23)28)13(2)24-18)17-10-8-16(9-11-17)15-6-4-14(5-7-15)12-19(26)27/h8-11,14-15H,3-7,12H2,1-2H3,(H2,23,28)(H,26,27)/t14-,15-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillography				J Med Chem 55: 10610-29 (2012) Article DOI: 10.1021/jm301296t BindingDB Entry DOI: 10.7270/Q2XD12T3
					More data for this Ligand-Target Pair