Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 2' and Ligand = 'BDBM323630'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323630 ((R)-2-(3-((2-(3-(2- ethoxyphenoxy)piperidin-1- yl)...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1cccc(CC(O)=O)c1 Show InChI InChI=1S/C27H30N4O5/c1-2-35-23-10-3-4-11-24(23)36-22-9-6-12-31(18-22)27-29-16-21(17-30-27)26(34)28-15-20-8-5-7-19(13-20)14-25(32)33/h3-5,7-8,10-11,13,16-17,22H,2,6,9,12,14-15,18H2,1H3,(H,28,34)(H,32,33)/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323630 ((R)-2-(3-((2-(3-(2- ethoxyphenoxy)piperidin-1- yl)...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1cccc(CC(O)=O)c1 Show InChI InChI=1S/C27H30N4O5/c1-2-35-23-10-3-4-11-24(23)36-22-9-6-12-31(18-22)27-29-16-21(17-30-27)26(34)28-15-20-8-5-7-19(13-20)14-25(32)33/h3-5,7-8,10-11,13,16-17,22H,2,6,9,12,14-15,18H2,1H3,(H,28,34)(H,32,33)/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US10188653 (2019) BindingDB Entry DOI: 10.7270/Q28G8NS4
					More data for this Ligand-Target Pair