Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 2' and Ligand = 'BDBM323641'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323641 ((R)-N-(2-(1H-1,2,4-triazol- 1-yl)ethyl)-2-(3-(2- e...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCCn1cncn1 Show InChI InChI=1S/C22H27N7O3/c1-2-31-19-7-3-4-8-20(19)32-18-6-5-10-28(14-18)22-25-12-17(13-26-22)21(30)24-9-11-29-16-23-15-27-29/h3-4,7-8,12-13,15-16,18H,2,5-6,9-11,14H2,1H3,(H,24,30)/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32.4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323641 ((R)-N-(2-(1H-1,2,4-triazol- 1-yl)ethyl)-2-(3-(2- e...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCCn1cncn1 Show InChI InChI=1S/C22H27N7O3/c1-2-31-19-7-3-4-8-20(19)32-18-6-5-10-28(14-18)22-25-12-17(13-26-22)21(30)24-9-11-29-16-23-15-27-29/h3-4,7-8,12-13,15-16,18H,2,5-6,9-11,14H2,1H3,(H,24,30)/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32.4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US10188653 (2019) BindingDB Entry DOI: 10.7270/Q28G8NS4
					More data for this Ligand-Target Pair