Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 2' and Ligand = 'BDBM323655'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323655 ((R)-N-cyclobutyl-2-(3-(2- ethoxyphenoxy)piperidin-...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NC1CCC1 Show InChI InChI=1S/C22H28N4O3/c1-2-28-19-10-3-4-11-20(19)29-18-9-6-12-26(15-18)22-23-13-16(14-24-22)21(27)25-17-7-5-8-17/h3-4,10-11,13-14,17-18H,2,5-9,12,15H2,1H3,(H,25,27)/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323655 ((R)-N-cyclobutyl-2-(3-(2- ethoxyphenoxy)piperidin-...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NC1CCC1 Show InChI InChI=1S/C22H28N4O3/c1-2-28-19-10-3-4-11-20(19)29-18-9-6-12-26(15-18)22-23-13-16(14-24-22)21(27)25-17-7-5-8-17/h3-4,10-11,13-14,17-18H,2,5-9,12,15H2,1H3,(H,25,27)/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US10188653 (2019) BindingDB Entry DOI: 10.7270/Q28G8NS4
					More data for this Ligand-Target Pair