Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Diacylglycerol kinase alpha (Homo sapiens) | BDBM43868 (3-[2-[4-[bis(4-fluorophenyl)methylene]piperidino]e...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres... | Eur J Med Chem 164: 378-390 (2019) Article DOI: 10.1016/j.ejmech.2018.12.061 BindingDB Entry DOI: 10.7270/Q2N01B01 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol kinase alpha (Homo sapiens) | BDBM43868 (3-[2-[4-[bis(4-fluorophenyl)methylene]piperidino]e...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres... | Eur J Med Chem 164: 378-390 (2019) Article DOI: 10.1016/j.ejmech.2018.12.061 BindingDB Entry DOI: 10.7270/Q2N01B01 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol kinase alpha (Homo sapiens) | BDBM43868 (3-[2-[4-[bis(4-fluorophenyl)methylene]piperidino]e...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates using DAG as substrate measured after 5 mins in presence of [ga... | Eur J Med Chem 164: 378-390 (2019) Article DOI: 10.1016/j.ejmech.2018.12.061 BindingDB Entry DOI: 10.7270/Q2N01B01 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol kinase alpha (Homo sapiens) | BDBM43868 (3-[2-[4-[bis(4-fluorophenyl)methylene]piperidino]e...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates using DAG as substrate measured after 5 mins in presence of [ga... | Eur J Med Chem 164: 378-390 (2019) Article DOI: 10.1016/j.ejmech.2018.12.061 BindingDB Entry DOI: 10.7270/Q2N01B01 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol kinase alpha (Sus scrofa) | BDBM43868 (3-[2-[4-[bis(4-fluorophenyl)methylene]piperidino]e...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of pig FLAG3-tagged DGKalpha expressed in African green monkey COS7 cells using 1,2-dioleoyl-sn-glycerol as substrate measured after 30 mi... | Eur J Med Chem 164: 378-390 (2019) Article DOI: 10.1016/j.ejmech.2018.12.061 BindingDB Entry DOI: 10.7270/Q2N01B01 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol kinase alpha (Sus scrofa) | BDBM43868 (3-[2-[4-[bis(4-fluorophenyl)methylene]piperidino]e...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of pig FLAG3-tagged DGKalpha expressed in African green monkey COS7 cells using 1,2-dioleoyl-sn-glycerol as substrate measured after 30 mi... | Eur J Med Chem 164: 378-390 (2019) Article DOI: 10.1016/j.ejmech.2018.12.061 BindingDB Entry DOI: 10.7270/Q2N01B01 | |||||||||||
More data for this Ligand-Target Pair |