Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dickkopf-related protein 1' and Ligand = 'BDBM50303036'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dickkopf-related protein 1 (Homo sapiens (Human))	BDBM50303036 (CHEMBL569986 | N-((1-(4-(naphthalen-2-yl)pyrimidin...) Show SMILES CC(=O)NCC1CCN(CC1)c1nccc(n1)-c1ccc2ccccc2c1 Show InChI InChI=1S/C22H24N4O/c1-16(27)24-15-17-9-12-26(13-10-17)22-23-11-8-21(25-22)20-7-6-18-4-2-3-5-19(18)14-20/h2-8,11,14,17H,9-10,12-13,15H2,1H3,(H,24,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of Dkk1-mediated Wnt/beta-catenin signaling in osteosasrcoma cells assessed as potentiation of TCF-luciferase response				J Med Chem 52: 6962-5 (2009) Article DOI: 10.1021/jm9014197 BindingDB Entry DOI: 10.7270/Q2HM58JV
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