Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dihydroorotate dehydrogenase (quinone), mitochondrial' and Ligand = 'BDBM102477'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM102477 (US8536165, 74) Show SMILES Cc1cc(Nc2ccc(cc2C(O)=O)C2CC2)cnc1-c1ccccc1 Show InChI InChI=1S/C22H20N2O2/c1-14-11-18(13-23-21(14)16-5-3-2-4-6-16)24-20-10-9-17(15-7-8-15)12-19(20)22(25)26/h2-6,9-13,15,24H,7-8H2,1H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	8.0	n/a
Almirall, S.A. US Patent					Assay Description Inhibition of human DHODH activity assay: DHODH activity and its inhibition were studied using a chromogen reduction assay with DCIP (2,6-dichloroph...				US Patent US8536165 (2013) BindingDB Entry DOI: 10.7270/Q2C24V2G
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