Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dihydroorotate dehydrogenase (quinone), mitochondrial' and Ligand = 'BDBM155409'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM155409 (US9006454, I19) Show SMILES OC(=O)c1cccc2nc(oc12)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H13NO3/c22-20(23)16-7-4-8-17-18(16)24-19(21-17)15-11-9-14(10-12-15)13-5-2-1-3-6-13/h1-12H,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.03E+3	n/a	n/a	n/a	n/a	8.0	n/a
Merck Serono S.A. US Patent					Assay Description The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...				US Patent US9006454 (2015) BindingDB Entry DOI: 10.7270/Q2125RCJ
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