Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dihydroorotate dehydrogenase (quinone), mitochondrial' and Ligand = 'BDBM490467'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM490467 (2-[(1S)-1-cyclohexylethoxy]-5-fluoro-N-(4-methylpy...) Show SMILES C[C@H](Oc1cc(c(F)cc1C(=O)Nc1nnccc1C)-n1nc2CCCCn2c1=O)C1CCCCC1 |r| Show InChI InChI=1S/C26H31FN6O3/c1-16-11-12-28-30-24(16)29-25(34)19-14-20(27)21(33-26(35)32-13-7-6-10-23(32)31-33)15-22(19)36-17(2)18-8-4-3-5-9-18/h11-12,14-15,17-18H,3-10,13H2,1-2H3,(H,29,30,34)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
BAYER AKTIENGESELLSCHAFT; BAYER PHARMA AKTIENGESELLSCHAFT; THE BROAD INSTITUTE, INC.; PRESIDENT AND FELLOWS OF HARVARD COLLEGE; THE GENERAL HOSPITAL CORPORATION US Patent					Assay Description Assay—1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...				US Patent US10968216 (2021) BindingDB Entry DOI: 10.7270/Q2WM1HJN
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