Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dihydroorotate dehydrogenase (quinone), mitochondrial' and Ligand = 'BDBM50071390'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071390 (5-tert-Butyl-isoxazole-4-carbothioic acid (4-cyano...) Show SMILES CC(C)(C)c1oncc1C(=S)Nc1ccc(cc1)C#N Show InChI InChI=1S/C15H15N3OS/c1-15(2,3)13-12(9-17-19-13)14(20)18-11-6-4-10(8-16)5-7-11/h4-7,9H,1-3H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair