Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dihydroorotate dehydrogenase (quinone), mitochondrial' and Ligand = 'BDBM50096198'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50096198 (CHEMBL3593804) Show SMILES CC(=O)Nc1ccccc1COc1ccc(cc1)-c1ccc(cc1)-c1nc2c(cc(C)cc2[nH]1)C(O)=O Show InChI InChI=1S/C36H53N5O5/c1-6-24(3)15-9-8-10-17-28-34(43)38-29(21-26-22-41(46-5)30-18-12-11-16-27(26)30)35(44)39-33(25(4)7-2)32(42)23-40-20-14-13-19-31(40)36(45)37-28/h11-12,16,18,22,25,28-29,31,33H,3,6-10,13-15,17,19-21,23H2,1-2,4-5H3,(H,37,45)(H,38,43)(H,39,44)/t25?,28-,29-,31+,33-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Malaya Curated by ChEMBL					Assay Description Inhibition of DHODH (unknown origin) using L-DHO, DUQ, DCIP as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...				Bioorg Med Chem 23: 4669-80 (2015) Article DOI: 10.1016/j.bmc.2015.05.051 BindingDB Entry DOI: 10.7270/Q2S75J2K
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