Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dihydroorotate dehydrogenase (quinone), mitochondrial' and Ligand = 'BDBM8661'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM8661 (US8536165, 110) Show SMILES Cc1ccc(Nc2ccc(nc2)-c2ccc(F)cc2F)c(c1)C(O)=O Show InChI InChI=1S/C19H14F2N2O2/c1-11-2-6-18(15(8-11)19(24)25)23-13-4-7-17(22-10-13)14-5-3-12(20)9-16(14)21/h2-10,23H,1H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
Almirall, S.A. US Patent					Assay Description Inhibition of human DHODH activity assay: DHODH activity and its inhibition were studied using a chromogen reduction assay with DCIP (2,6-dichloroph...				US Patent US8536165 (2013) BindingDB Entry DOI: 10.7270/Q2C24V2G
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