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Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Gag-Pol polyprotein [489-587]' and Ligand = 'BDBM1165'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dimer of Gag-Pol polyprotein [489-587]


(Human immunodeficiency virus type 1)		BDBM1165
PNG
((4R,5S,6S,7R)-1,3-Bis{[4-(methoxycarbonyl)phenyl]m...)
Show SMILES COC(=O)c1ccc(CN2[C@H](COc3ccccc3)[C@H](O)[C@@H](O)[C@@H](COc3ccccc3)N(Cc3ccc(cc3)C(=O)OC)C2=O)cc1 |r|
Show InChI InChI=1S/C37H38N2O9/c1-45-35(42)27-17-13-25(14-18-27)21-38-31(23-47-29-9-5-3-6-10-29)33(40)34(41)32(24-48-30-11-7-4-8-12-30)39(37(38)44)22-26-15-19-28(20-16-26)36(43)46-2/h3-20,31-34,40-41H,21-24H2,1-2H3/t31-,32-,33+,34+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 8.00E+3n/an/an/an/a5.537



Uppsala University



Assay Description
The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...

J Med Chem 40: 885-97 (1997)


Article DOI: 10.1021/jm960728j
BindingDB Entry DOI: 10.7270/Q24B2ZGX
More data for this
Ligand-Target Pair