Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Gag-Pol polyprotein [489-587]' and Ligand = 'BDBM906'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM906 ((4S,5S)-5-[(2S)-2-[(2S)-2-aminopropanamido]propana...) Show SMILES C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CCC(=O)NC(c1nc2ccccc2[nH]1)c1ccccc1 |r| Show InChI InChI=1S/C32H38N6O4/c1-20(33)31(41)34-21(2)32(42)37-26(19-22-11-5-3-6-12-22)27(39)17-18-28(40)38-29(23-13-7-4-8-14-23)30-35-24-15-9-10-16-25(24)36-30/h3-16,20-21,26-27,29,39H,17-19,33H2,1-2H3,(H,34,41)(H,35,36)(H,37,42)(H,38,40)/t20-,21-,26-,27-,29?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	5.37E+3	-31.3	n/a	n/a	n/a	n/a	n/a	5.5	37
Agouron Pharmaceuticals, Inc.					Assay Description Protease activity was measured by continuous chromogenic assay. The chromogenic peptide His-Lys-Ala-Arg-Val-Leu- (p-NO2-Phe)-Glu-Ala-Nleu-Ser (Bache...				J Med Chem 37: 2274-84 (1994) Article DOI: 10.1021/jm00041a005 BindingDB Entry DOI: 10.7270/Q29021XP
					More data for this Ligand-Target Pair