BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Gag-Pol polyprotein [501-599]' and Ligand = 'BDBM9846'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9846
PNG
(3-[(5S)-5-[(4-aminobenzene)(3-methylbutyl)sulfonam...)
Show SMILES CC(C)CCN([C@H](CO)CCCCNC(=O)N(Cc1ccc(F)cc1)Cc1ccc2OCCOc2c1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C34H45FN4O6S/c1-25(2)16-18-39(46(42,43)31-13-11-29(36)12-14-31)30(24-40)5-3-4-17-37-34(41)38(22-26-6-9-28(35)10-7-26)23-27-8-15-32-33(21-27)45-20-19-44-32/h6-15,21,25,30,40H,3-5,16-20,22-24,36H2,1-2H3,(H,37,41)/t30-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
 5.40n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair