Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM14014 ((5S)-31-oxo-20-oxa-2,6,11,13-tetraazahexacyclo[19....) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibitory concentration against farnesyltransferase was determined | J Med Chem 47: 1869-78 (2004) Article DOI: 10.1021/jm0305467 BindingDB Entry DOI: 10.7270/Q2RX9CVX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |