Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50058207'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058207 ((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-nap...) Show SMILES CSCC[C@H](N(C)C(=O)c1cccc2c(NC[C@@H](N)CS)cccc12)C(O)=O Show InChI InChI=1S/C20H27N3O3S2/c1-23(18(20(25)26)9-10-28-2)19(24)16-7-3-6-15-14(16)5-4-8-17(15)22-11-13(21)12-27/h3-8,13,18,22,27H,9-12,21H2,1-2H3,(H,25,26)/t13-,18+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair