Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50061450'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50061450 (1-[(2R,3R)-3-(2-Chloro-thiophen-3-ylmethoxy)-2,3-d...) Show SMILES Clc1sccc1CO[C@H]1[C@@H](Cn2ccnc2)Sc2ccccc12 Show InChI InChI=1S/C17H15ClN2OS2/c18-17-12(5-8-22-17)10-21-16-13-3-1-2-4-14(13)23-15(16)9-20-7-6-19-11-20/h1-8,11,15-16H,9-10H2/t15-,16-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human farnesyltransferase				J Med Chem 40: 4103-12 (1998) Article DOI: 10.1021/jm970291v BindingDB Entry DOI: 10.7270/Q2T152R0
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