Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50061482'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50061482 (1-[(2R,3R)-3-(2,6-Dichloro-benzyloxy)-5-fluoro-2,3...) Show SMILES Fc1ccc2S[C@H](Cn3ccnc3)[C@H](OCc3c(Cl)cccc3Cl)c2c1 Show InChI InChI=1S/C19H15Cl2FN2OS/c20-15-2-1-3-16(21)14(15)10-25-19-13-8-12(22)4-5-17(13)26-18(19)9-24-7-6-23-11-24/h1-8,11,18-19H,9-10H2/t18-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human farnesyltransferase				J Med Chem 40: 4103-12 (1998) Article DOI: 10.1021/jm970291v BindingDB Entry DOI: 10.7270/Q2T152R0
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