Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50063351'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50063351 (1-[(S)-4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5...) Show SMILES CCCC[C@H]1CN(CCN1C(=O)Cc1cc[n+]([O-])cc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C29H32BrClN4O2/c1-2-3-4-25-19-33(13-14-35(25)27(36)15-20-9-11-34(37)12-10-20)29-26-8-7-24(31)17-21(26)5-6-22-16-23(30)18-32-28(22)29/h7-12,16-18,25,29H,2-6,13-15,19H2,1H3/t25-,29?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of farnesyltransferase farnesylation of the H-ras oncogene				J Med Chem 41: 877-93 (1998) Article DOI: 10.1021/jm970462w BindingDB Entry DOI: 10.7270/Q2M61JDN
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50063351 (1-[(S)-4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5...) Show SMILES CCCC[C@H]1CN(CCN1C(=O)Cc1cc[n+]([O-])cc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C29H32BrClN4O2/c1-2-3-4-25-19-33(13-14-35(25)27(36)15-20-9-11-34(37)12-10-20)29-26-8-7-24(31)17-21(26)5-6-22-16-23(30)18-32-28(22)29/h7-12,16-18,25,29H,2-6,13-15,19H2,1H3/t25-,29?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Farnesyltransferase from Ras-CVLS or Ras-CVLL in Cos-7 monkey kidney cells				J Med Chem 41: 877-93 (1998) Article DOI: 10.1021/jm970462w BindingDB Entry DOI: 10.7270/Q2M61JDN
					More data for this Ligand-Target Pair