Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50063415'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50063415 (4-{2-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,...) Show SMILES CNC(=O)N1CCC(CC(=O)N2CCN(CC2)C2c3ccc(Cl)cc3CCc3cc(Br)cnc23)CC1 Show InChI InChI=1S/C27H33BrClN5O2/c1-30-27(36)34-8-6-18(7-9-34)14-24(35)32-10-12-33(13-11-32)26-23-5-4-22(29)16-19(23)2-3-20-15-21(28)17-31-25(20)26/h4-5,15-18,26H,2-3,6-14H2,1H3,(H,30,36)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of farnesyltransferase farnesylation of the H-ras oncogene				J Med Chem 41: 877-93 (1998) Article DOI: 10.1021/jm970462w BindingDB Entry DOI: 10.7270/Q2M61JDN
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50063415 (4-{2-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,...) Show SMILES CNC(=O)N1CCC(CC(=O)N2CCN(CC2)C2c3ccc(Cl)cc3CCc3cc(Br)cnc23)CC1 Show InChI InChI=1S/C27H33BrClN5O2/c1-30-27(36)34-8-6-18(7-9-34)14-24(35)32-10-12-33(13-11-32)26-23-5-4-22(29)16-19(23)2-3-20-15-21(28)17-31-25(20)26/h4-5,15-18,26H,2-3,6-14H2,1H3,(H,30,36)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Farnesyltransferase from Ras-CVLS or Ras-CVLL in Cos-7 monkey kidney cells				J Med Chem 41: 877-93 (1998) Article DOI: 10.1021/jm970462w BindingDB Entry DOI: 10.7270/Q2M61JDN
					More data for this Ligand-Target Pair