Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50076137'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50076137 ((S)-2-({3-[(1H-Imidazol-4-ylmethyl)-amino]-bipheny...) Show SMILES CC(C)C[C@H](NC(=O)c1c(NCc2cnc[nH]2)cccc1-c1ccccc1)C(O)=O Show InChI InChI=1S/C23H26N4O3/c1-15(2)11-20(23(29)30)27-22(28)21-18(16-7-4-3-5-8-16)9-6-10-19(21)25-13-17-12-24-14-26-17/h3-10,12,14-15,20,25H,11,13H2,1-2H3,(H,24,26)(H,27,28)(H,29,30)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-FPP incorporation into H-Ras-CVLS by Farnesyl transferase				J Med Chem 42: 1333-40 (1999) Article DOI: 10.1021/jm9900873 BindingDB Entry DOI: 10.7270/Q28G8JW7
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