Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50081218'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50081218 ((S)-4-((5-((4-(1-naphthoyl)-2-butylpiperazin-1-yl)...) Show SMILES CCCC[C@H]1CN(CCN1Cc1cncn1Cc1ccc(cc1)C#N)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C31H33N5O/c1-2-3-9-27-21-35(31(37)30-11-6-8-26-7-4-5-10-29(26)30)17-16-34(27)22-28-19-33-23-36(28)20-25-14-12-24(18-32)13-15-25/h4-8,10-15,19,23,27H,2-3,9,16-17,20-22H2,1H3/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into recombinant human K-Ras by Farnesyltransferase				J Med Chem 42: 3779-84 (1999) BindingDB Entry DOI: 10.7270/Q2F47NB1
					More data for this Ligand-Target Pair