Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50092373'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50092373 (3-Benzyl-7-cyano-1-(3H-imidazol-4-ylmethyl)-1,2,3,...) Show SMILES CCOC(=O)N1Cc2cc(ccc2N(Cc2cnc[nH]2)C[C@H]1Cc1ccccc1)C#N Show InChI InChI=1S/C24H25N5O2/c1-2-31-24(30)29-14-20-10-19(12-25)8-9-23(20)28(15-21-13-26-17-27-21)16-22(29)11-18-6-4-3-5-7-18/h3-10,13,17,22H,2,11,14-16H2,1H3,(H,26,27)/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of purified recombinant human farnesyltransferase (FT)				J Med Chem 43: 3587-95 (2000) BindingDB Entry DOI: 10.7270/Q2WD3ZSV
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