Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50092379'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50092379 (7-Bromo-1-(3H-imidazol-4-ylmethyl)-4-methanesulfon...) Show SMILES COc1ccc(CC2CN(Cc3cnc[nH]3)c3ccc(Br)cc3CN2S(C)(=O)=O)cc1 Show InChI InChI=1S/C22H25BrN4O3S/c1-30-21-6-3-16(4-7-21)9-20-14-26(13-19-11-24-15-25-19)22-8-5-18(23)10-17(22)12-27(20)31(2,28)29/h3-8,10-11,15,20H,9,12-14H2,1-2H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of purified recombinant human farnesyltransferase (FT)				J Med Chem 43: 3587-95 (2000) BindingDB Entry DOI: 10.7270/Q2WD3ZSV
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