Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50108069'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50108069 (4'-[(3H-Imidazol-4-ylmethyl)-amino]-[1,1';2',1'']t...) Show SMILES COC(=O)c1cccc(c1)-c1ccc(NCc2cnc[nH]2)cc1-c1ccccc1 Show InChI InChI=1S/C24H21N3O2/c1-29-24(28)19-9-5-8-18(12-19)22-11-10-20(26-15-21-14-25-16-27-21)13-23(22)17-6-3-2-4-7-17/h2-14,16,26H,15H2,1H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of farnesyltransferase from human Burkitt lymphoma (Daudi) cells				J Med Chem 45: 177-88 (2001) BindingDB Entry DOI: 10.7270/Q22F7MQ7
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