Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50108072'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50108072 (4'-(2-Mercapto-benzylamino)-[1,1';2',1'']terphenyl...) Show SMILES COC(=O)c1cccc(c1)-c1ccc(NCc2ccccc2S)cc1-c1ccccc1 Show InChI InChI=1S/C27H23NO2S/c1-30-27(29)21-12-7-11-20(16-21)24-15-14-23(17-25(24)19-8-3-2-4-9-19)28-18-22-10-5-6-13-26(22)31/h2-17,28,31H,18H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of farnesyltransferase from human Burkitt lymphoma (Daudi) cells				J Med Chem 45: 177-88 (2001) BindingDB Entry DOI: 10.7270/Q22F7MQ7
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