Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50117935'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50117935 ((+)4-{2-[4-(4-chloro-3,6,7,12-tetrahydropyrido[2',...) Show SMILES [O-][n+]1ccc(CC(=O)N2CCC(CC2)C2c3ncccc3CCc3cc(Cl)c4[nH]ccc4c23)cc1 Show InChI InChI=1S/C28H27ClN4O2/c29-23-17-21-4-3-20-2-1-10-30-27(20)26(25(21)22-5-11-31-28(22)23)19-8-12-32(13-9-19)24(34)16-18-6-14-33(35)15-7-18/h1-2,5-7,10-11,14-15,17,19,26,31H,3-4,8-9,12-13,16H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val				J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB
					More data for this Ligand-Target Pair