Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 2' and Ligand = 'BDBM50137252'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50137252 (CHEMBL3084943 | N-[4-((S)-1-Amino-2-oxo-2-thiazoli...) Show SMILES [H][C@@]1(CC[C@@H](CC1)NS(=O)(=O)c1ccc(F)c(F)c1F)[C@H](N)C(=O)N1CCSC1 |wU:4.7,1.0,wD:20.22,(1.73,2.31,;3.07,1.54,;1.75,.76,;1.75,-.78,;3.07,-1.54,;4.4,-.78,;4.4,.76,;3.07,-3.09,;4.42,-3.86,;4.42,-5.4,;5.75,-3.09,;5.75,-4.63,;7.07,-3.86,;8.4,-4.61,;8.4,-6.17,;9.73,-6.94,;7.07,-6.93,;7.07,-8.47,;5.74,-6.16,;4.4,-6.93,;3.07,3.09,;1.74,3.86,;4.42,3.87,;4.42,5.42,;5.75,3.09,;7.16,3.72,;8.19,2.57,;7.42,1.23,;5.92,1.56,)| Show InChI InChI=1S/C17H22F3N3O3S2/c18-12-5-6-13(15(20)14(12)19)28(25,26)22-11-3-1-10(2-4-11)16(21)17(24)23-7-8-27-9-23/h5-6,10-11,16,22H,1-4,7-9,21H2/t10-,11-,16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Inc. Curated by ChEMBL					Assay Description Inhibitory activity against quiescent cell prolyl peptidase (QPP).				Bioorg Med Chem Lett 14: 43-6 (2003) BindingDB Entry DOI: 10.7270/Q26972ZM
					More data for this Ligand-Target Pair