Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 4' and Ligand = 'BDBM162381'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM162381 (US9051329, Example 6) Show SMILES CCN1C(=O)Cn2c1nc1nc(N3CCC[C@H](C3)NC(=O)OC(C)(C)C)n(Cc3cc(F)ccc3C#N)c1c2=O |r| Show InChI InChI=1S/C27H31FN8O4/c1-5-34-20(37)15-36-23(38)21-22(32-25(34)36)31-24(35(21)13-17-11-18(28)9-8-16(17)12-29)33-10-6-7-19(14-33)30-26(39)40-27(2,3)4/h8-9,11,19H,5-7,10,13-15H2,1-4H3,(H,30,39)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13.5	n/a	n/a	n/a	n/a	7.5	37
Merck Sharp & Dohme Corp. US Patent					Assay Description DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...				US Patent US9051329 (2015) BindingDB Entry DOI: 10.7270/Q2S46QP2
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