Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 4' and Ligand = 'BDBM224586'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224586 (US10202383, Example 2(66) | US9321791, 2(66) | US9...) Show SMILES [#6]-[#8]-c1cccc(-[#6](=O)-[#6]-n2c(=O)n(-[#6])c3nc(-[#7]-4-[#6]-[#6]-[#6]-[#6](-[#7])-[#6]-4)n(-[#6]\[#6]=[#6](\[#6])-[#6])c3c2=O)c1-[#8]-[#6] Show InChI InChI=1S/C26H34N6O5/c1-16(2)11-13-31-21-23(28-25(31)30-12-7-8-17(27)14-30)29(3)26(35)32(24(21)34)15-19(33)18-9-6-10-20(36-4)22(18)37-5/h6,9-11,17H,7-8,12-15,27H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	7.8	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates. 20 ...				US Patent US9321791 (2016) BindingDB Entry DOI: 10.7270/Q2GQ6WNR
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224586 (US10202383, Example 2(66) | US9321791, 2(66) | US9...) Show SMILES [#6]-[#8]-c1cccc(-[#6](=O)-[#6]-n2c(=O)n(-[#6])c3nc(-[#7]-4-[#6]-[#6]-[#6]-[#6](-[#7])-[#6]-4)n(-[#6]\[#6]=[#6](\[#6])-[#6])c3c2=O)c1-[#8]-[#6] Show InChI InChI=1S/C26H34N6O5/c1-16(2)11-13-31-21-23(28-25(31)30-12-7-8-17(27)14-30)29(3)26(35)32(24(21)34)15-19(33)18-9-6-10-20(36-4)22(18)37-5/h6,9-11,17H,7-8,12-15,27H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....				US Patent US10202383 (2019) BindingDB Entry DOI: 10.7270/Q2P55QNN
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224586 (US10202383, Example 2(66) | US9321791, 2(66) | US9...) Show SMILES [#6]-[#8]-c1cccc(-[#6](=O)-[#6]-n2c(=O)n(-[#6])c3nc(-[#7]-4-[#6]-[#6]-[#6]-[#6](-[#7])-[#6]-4)n(-[#6]\[#6]=[#6](\[#6])-[#6])c3c2=O)c1-[#8]-[#6] Show InChI InChI=1S/C26H34N6O5/c1-16(2)11-13-31-21-23(28-25(31)30-12-7-8-17(27)14-30)29(3)26(35)32(24(21)34)15-19(33)18-9-6-10-20(36-4)22(18)37-5/h6,9-11,17H,7-8,12-15,27H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	7.8	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....				US Patent US9556175 (2017) BindingDB Entry DOI: 10.7270/Q2Z03B5T
					More data for this Ligand-Target Pair