Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 8' and Ligand = 'BDBM50323188'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50323188 ((7-(2,4-dichlorophenyl)-5-methyl-2-(pyrrolidin-1-y...) Show SMILES Cc1nc2nc(nn2c(c1CN)-c1ccc(Cl)cc1Cl)N1CCCC1 |(43.1,-9.38,;41.77,-10.15,;40.43,-9.39,;39.1,-10.16,;37.62,-9.69,;36.73,-10.95,;37.64,-12.19,;39.11,-11.7,;40.44,-12.46,;41.77,-11.69,;43.11,-12.46,;44.44,-11.69,;40.45,-14,;39.12,-14.77,;39.12,-16.31,;40.45,-17.09,;40.45,-18.63,;41.79,-16.31,;41.78,-14.76,;43.11,-13.99,;35.19,-10.96,;34.28,-9.73,;32.81,-10.21,;32.83,-11.75,;34.29,-12.22,)| Show InChI InChI=1S/C17H18Cl2N6/c1-10-13(9-20)15(12-5-4-11(18)8-14(12)19)25-16(21-10)22-17(23-25)24-6-2-3-7-24/h4-5,8H,2-3,6-7,9,20H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human DPP8				Bioorg Med Chem Lett 20: 4395-8 (2010) Article DOI: 10.1016/j.bmcl.2010.06.063 BindingDB Entry DOI: 10.7270/Q27H1JS8
					More data for this Ligand-Target Pair