Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 8' and Ligand = 'BDBM50350167'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350167 (CHEMBL1814741) Show SMILES N[C@@H](CC(=O)N1CCN(CC1)C(c1ccccc1)c1ccc(Cl)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C29H31ClN4O2/c30-25-12-10-22(11-13-25)28(21-6-2-1-3-7-21)33-16-14-32(15-17-33)27(35)18-26(31)29(36)34-19-23-8-4-5-9-24(23)20-34/h1-13,26,28H,14-20,31H2/t26-,28?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Competitive inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min ...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350167 (CHEMBL1814741) Show SMILES N[C@@H](CC(=O)N1CCN(CC1)C(c1ccccc1)c1ccc(Cl)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C29H31ClN4O2/c30-25-12-10-22(11-13-25)28(21-6-2-1-3-7-21)33-16-14-32(15-17-33)27(35)18-26(31)29(36)34-19-23-8-4-5-9-24(23)20-34/h1-13,26,28H,14-20,31H2/t26-,28?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair