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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 8' and Ligand = 'BDBM50350180'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50350180
PNG
(CHEMBL1814756)
Show SMILES N[C@@H](CC(=O)N1CCC(CC1)N1CCCCC1)C(=O)N1Cc2ccccc2C1 |r|
Show InChI InChI=1S/C22H32N4O2/c23-20(22(28)26-15-17-6-2-3-7-18(17)16-26)14-21(27)25-12-8-19(9-13-25)24-10-4-1-5-11-24/h2-3,6-7,19-20H,1,4-5,8-16,23H2/t20-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 730n/an/an/an/an/an/a



University of Antwerp (UA)

Curated by ChEMBL


Assay Description
Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...

J Med Chem 54: 5737-46 (2011)


Article DOI: 10.1021/jm200383j
BindingDB Entry DOI: 10.7270/Q2G73F37
More data for this
Ligand-Target Pair