Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 8' and Ligand = 'BDBM50350182'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350182 (CHEMBL1814750) Show SMILES N[C@@H](CC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)C(=O)C1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C29H28F2N4O3/c30-23-9-5-19(6-10-23)28(20-7-11-24(31)12-8-20)35-14-13-33(18-27(35)37)26(36)15-25(32)29(38)34-16-21-3-1-2-4-22(21)17-34/h1-12,25,28H,13-18,32H2/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
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