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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 8' and Ligand = 'BDBM50350191'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50350191
PNG
(CHEMBL1814754)
Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1C(=O)N1CCN(CC1)C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 |r|
Show InChI InChI=1S/C34H37F2N5O3/c35-27-11-7-23(8-12-27)32(24-9-13-28(36)14-10-24)38-16-18-39(19-17-38)34(44)30-6-3-15-41(30)31(42)20-29(37)33(43)40-21-25-4-1-2-5-26(25)22-40/h1-2,4-5,7-14,29-30,32H,3,6,15-22,37H2/t29-,30-/m0/s1
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Similars
Article
PubMed
n/an/a 6.80E+3n/an/an/an/an/an/a



University of Antwerp (UA)

Curated by ChEMBL


Assay Description
Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...

J Med Chem 54: 5737-46 (2011)


Article DOI: 10.1021/jm200383j
BindingDB Entry DOI: 10.7270/Q2G73F37
More data for this
Ligand-Target Pair