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Found 1 hit Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 8' and Ligand = 'BDBM50443746'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50443746
PNG
(CHEMBL3093913)
Show SMILES N[C@@H](Cc1ccc(F)cc1F)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C14H14F3N3O/c15-9-2-1-8(12(17)5-9)3-13(19)14(21)20-7-10(16)4-11(20)6-18/h1-2,5,10-11,13H,3-4,7,19H2/t10-,11-,13-/m0/s1
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Similars
Article
PubMed
n/an/a 960n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of 6xHis-tagged recombinant DPP8 (unknown origin) expressed in baculovirus expression system assessed as hydrolysis of Ala-Pro-aminomethyl...

Bioorg Med Chem 21: 7418-29 (2013)


Article DOI: 10.1016/j.bmc.2013.09.048
BindingDB Entry DOI: 10.7270/Q2WS8VPZ
More data for this
Ligand-Target Pair