Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM50118984'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50118984 (4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-(2-meth...) Show SMILES COCC(=O)N1CC(N(Cc2ccccc12)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1)C(=O)NO Show InChI InChI=1S/C25H24ClN3O7S/c1-35-16-24(30)28-15-23(25(31)27-32)29(14-17-4-2-3-5-22(17)28)37(33,34)21-12-10-20(11-13-21)36-19-8-6-18(26)7-9-19/h2-13,23,32H,14-16H2,1H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	157	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Concentration required in vitro to inhibit TNF-alpha converting enzyme (TACE)				Bioorg Med Chem Lett 12: 2867-70 (2002) BindingDB Entry DOI: 10.7270/Q2JS9PSH
					More data for this Ligand-Target Pair