Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM50120697'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig))	BDBM50120697 (2-[3-(4-tert-Butoxy-phenyl)-3-methyl-2-oxo-pyrroli...) Show SMILES C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OC(C)(C)C)cc1)C(=O)NO Show InChI InChI=1S/C18H26N2O4/c1-12(15(21)19-23)20-11-10-18(5,16(20)22)13-6-8-14(9-7-13)24-17(2,3)4/h6-9,12,23H,10-11H2,1-5H3,(H,19,21)/t12-,18+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Affinity for Tumor necrosis factor alpha converting enzyme (TACE)				J Med Chem 45: 4954-7 (2002) BindingDB Entry DOI: 10.7270/Q2XP7497
					More data for this Ligand-Target Pair