Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM50167494'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50167494 (5-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-5-(4-...) Show SMILES Cc1cc(COc2ccc(cc2)C2(N3CCN(CCc4ccccc4)CC3)C(=O)NC(=O)NC2=O)c2ccccc2n1 Show InChI InChI=1S/C33H33N5O4/c1-23-21-25(28-9-5-6-10-29(28)34-23)22-42-27-13-11-26(12-14-27)33(30(39)35-32(41)36-31(33)40)38-19-17-37(18-20-38)16-15-24-7-3-2-4-8-24/h2-14,21H,15-20,22H2,1H3,(H2,35,36,39,40,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against human tumor necrosis factor-alpha converting enzyme				Bioorg Med Chem Lett 15: 2970-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.039 BindingDB Entry DOI: 10.7270/Q2028R2B
					More data for this Ligand-Target Pair