Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM50243094'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50243094 (CHEMBL4090901) Show SMILES COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3cc4nc(N5CC(=O)NC5=O)c(F)cc4o3)C(=O)c2c1F |r| Show InChI InChI=1S/C23H16F2N6O7/c1-37-12-3-2-9-6-30(19(33)16(9)17(12)25)8-23(20(34)28-21(35)29-23)14-5-11-13(38-14)4-10(24)18(26-11)31-7-15(32)27-22(31)36/h2-5H,6-8H2,1H3,(H,27,32,36)(H2,28,29,34,35)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of catalytic domain TACE (unknown origin) by FRET assay				Bioorg Med Chem Lett 27: 3037-3042 (2017) Article DOI: 10.1016/j.bmcl.2017.05.062 BindingDB Entry DOI: 10.7270/Q2319Z8G
					More data for this Ligand-Target Pair