Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM50313825'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50313825 ((+/-)-5-(4-fluorophenyl)-5-((1-oxoisoindolin-2-yl)...) Show SMILES Fc1ccc(cc1)C1(CN2Cc3ccccc3C2=O)NC(=O)NC1=O Show InChI InChI=1S/C18H14FN3O3/c19-13-7-5-12(6-8-13)18(16(24)20-17(25)21-18)10-22-9-11-3-1-2-4-14(11)15(22)23/h1-8H,9-10H2,(H2,20,21,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of TACE by FRET assay				Bioorg Med Chem Lett 20: 1877-80 (2010) Article DOI: 10.1016/j.bmcl.2010.01.148 BindingDB Entry DOI: 10.7270/Q2F76CQ9
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