BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM50332479'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50332479 (4-(4-(2-(Diethylamino)ethoxy)phenyl)-2-((7-fluoro-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Inhibition of human TACE by fluorescent spectroscopy				Bioorg Med Chem 18: 8618-29 (2010) Article DOI: 10.1016/j.bmc.2010.10.006 BindingDB Entry DOI: 10.7270/Q2NV9JHW
Yonsei University Curated by ChEMBL					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50332479 (4-(4-(2-(Diethylamino)ethoxy)phenyl)-2-((7-fluoro-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Inhibition of human TNF-alpha by fluorescent spectroscopy				Bioorg Med Chem 18: 8618-29 (2010) Article DOI: 10.1016/j.bmc.2010.10.006 BindingDB Entry DOI: 10.7270/Q2NV9JHW
Yonsei University Curated by ChEMBL					More data for this Ligand-Target Pair