Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q]' and Ligand = 'BDBM23474'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] (Homo sapiens (Human))	BDBM23474 (hydroxamate deriv., 66 | methyl (1R,2R)-1-[3-(but-...) Show SMILES COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCC#CC)c1 |r| Show InChI InChI=1S/C16H17NO5/c1-3-4-8-22-12-7-5-6-11(9-12)16(15(19)21-2)10-13(16)14(18)17-20/h5-7,9,13,20H,8,10H2,1-2H3,(H,17,18)/t13-,16-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.60E+3	-32.7	n/a	n/a	n/a	n/a	n/a	7.3	22
Schering-Plough Research Institute					Assay Description Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...				J Med Chem 51: 725-36 (2008) Article DOI: 10.1021/jm070376o BindingDB Entry DOI: 10.7270/Q2Q23XKR
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