Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q]' and Ligand = 'BDBM23486'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] (Homo sapiens (Human))	BDBM23486 ((1R,2S)-1-{[4-(benzyloxy)phenyl]methyl}-2-N-hydrox...) Show SMILES NC(=O)[C@@]1(Cc2ccc(OCc3ccccc3)cc2)C[C@@H]1C(=O)NO |r| Show InChI InChI=1S/C19H20N2O4/c20-18(23)19(11-16(19)17(22)21-24)10-13-6-8-15(9-7-13)25-12-14-4-2-1-3-5-14/h1-9,16,24H,10-12H2,(H2,20,23)(H,21,22)/t16-,19+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute					Assay Description Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...				J Med Chem 51: 725-36 (2008) Article DOI: 10.1021/jm070376o BindingDB Entry DOI: 10.7270/Q2Q23XKR
					More data for this Ligand-Target Pair