Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase TTK' and Ligand = 'BDBM241288'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase TTK (Homo sapiens (Human))	BDBM241288 (US10479788, Example 130 | US11046688, Example 130 ...) Show SMILES COc1cc(ccc1Nc1ncc2ccnc(NC(CO)CO)c2n1)-c1cnn(C)c1 Show InChI InChI=1S/C21H23N7O3/c1-28-10-15(9-24-28)13-3-4-17(18(7-13)31-2)26-21-23-8-14-5-6-22-20(19(14)27-21)25-16(11-29)12-30/h3-10,16,29-30H,11-12H2,1-2H3,(H,22,25)(H,23,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...				US Patent US10479788 (2019) BindingDB Entry DOI: 10.7270/Q2BP055X
					More data for this Ligand-Target Pair
Dual specificity protein kinase TTK (Homo sapiens (Human))	BDBM241288 (US10479788, Example 130 | US11046688, Example 130 ...) Show SMILES COc1cc(ccc1Nc1ncc2ccnc(NC(CO)CO)c2n1)-c1cnn(C)c1 Show InChI InChI=1S/C21H23N7O3/c1-28-10-15(9-24-28)13-3-4-17(18(7-13)31-2)26-21-23-8-14-5-6-22-20(19(14)27-21)25-16(11-29)12-30/h3-10,16,29-30H,11-12H2,1-2H3,(H,22,25)(H,23,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.0	25
Cancer Research Technology Limited US Patent					Assay Description The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...				US Patent US9409907 (2016) BindingDB Entry DOI: 10.7270/Q2C24VB2
					More data for this Ligand-Target Pair