Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity protein phosphatase 1 (Homo sapiens (Human)) | BDBM31883 (9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | 2.71E+4 | n/a | n/a | n/a | n/a | 7.0 | 22 |
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay | Assay Description The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2F769WQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 1 (Homo sapiens (Human)) | BDBM31883 (9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | 4.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay | Assay Description The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit... | PubChem Bioassay (2006) BindingDB Entry DOI: 10.7270/Q2QR4VH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 1 (Homo sapiens (Human)) | BDBM31883 (9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | 4.86E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay | Assay Description The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1... | PubChem Bioassay (2006) BindingDB Entry DOI: 10.7270/Q2VH5M71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 1 (Homo sapiens (Human)) | BDBM31883 (9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | 4.86E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay | Assay Description The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi... | PubChem Bioassay (2006) BindingDB Entry DOI: 10.7270/Q20863PV | |||||||||||
More data for this Ligand-Target Pair |