Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Dual specificity protein phosphatase 1' and Ligand = 'BDBM35394'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein phosphatase 1 (Homo sapiens (Human))	BDBM35394 (6-chloranyl-N-[2-(cyclohexen-1-yl)ethyl]-5-methyl-...) Show SMILES Cc1nc2c(c[nH]n2c(=O)c1Cl)C(=O)NCCC1=CCCCC1 |t:19| Show InChI InChI=1S/C16H19ClN4O2/c1-10-13(17)16(23)21-14(20-10)12(9-19-21)15(22)18-8-7-11-5-3-2-4-6-11/h5,9,19H,2-4,6-8H2,1H3,(H,18,22)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.11E+4	n/a	n/a	n/a	n/a	7.0	22
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2F769WQ
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 1 (Homo sapiens (Human))	BDBM35394 (6-chloranyl-N-[2-(cyclohexen-1-yl)ethyl]-5-methyl-...) Show SMILES Cc1nc2c(c[nH]n2c(=O)c1Cl)C(=O)NCCC1=CCCCC1 |t:19| Show InChI InChI=1S/C16H19ClN4O2/c1-10-13(17)16(23)21-14(20-10)12(9-19-21)15(22)18-8-7-11-5-3-2-4-6-11/h5,9,19H,2-4,6-8H2,1H3,(H,18,22)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...				PubChem Bioassay (2006) BindingDB Entry DOI: 10.7270/Q2QR4VH9
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 1 (Homo sapiens (Human))	BDBM35394 (6-chloranyl-N-[2-(cyclohexen-1-yl)ethyl]-5-methyl-...) Show SMILES Cc1nc2c(c[nH]n2c(=O)c1Cl)C(=O)NCCC1=CCCCC1 |t:19| Show InChI InChI=1S/C16H19ClN4O2/c1-10-13(17)16(23)21-14(20-10)12(9-19-21)15(22)18-8-7-11-5-3-2-4-6-11/h5,9,19H,2-4,6-8H2,1H3,(H,18,22)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...				PubChem Bioassay (2006) BindingDB Entry DOI: 10.7270/Q2VH5M71
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 1 (Homo sapiens (Human))	BDBM35394 (6-chloranyl-N-[2-(cyclohexen-1-yl)ethyl]-5-methyl-...) Show SMILES Cc1nc2c(c[nH]n2c(=O)c1Cl)C(=O)NCCC1=CCCCC1 |t:19| Show InChI InChI=1S/C16H19ClN4O2/c1-10-13(17)16(23)21-14(20-10)12(9-19-21)15(22)18-8-7-11-5-3-2-4-6-11/h5,9,19H,2-4,6-8H2,1H3,(H,18,22)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...				PubChem Bioassay (2006) BindingDB Entry DOI: 10.7270/Q20863PV
					More data for this Ligand-Target Pair