Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1A' and Ligand = 'BDBM293619'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM293619 (US10106527, Compound 391 | US10544128, Compound 39...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1nncs1 Show InChI InChI=1S/C22H21N7OS/c1-28-6-8-29(9-7-28)20-12-15(4-5-23-20)21(30)26-19-11-18-10-16(22-27-25-14-31-22)2-3-17(18)13-24-19/h2-5,10-14H,6-9H2,1H3,(H,24,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	25
Samumed, LLC US Patent					Assay Description Briefly, recombinant DYRK1A kinase, ATP and Ser/Thr peptide 18 were prepared in 1× Kinase buffer to final concentrations of 0.19 μg/mL, 30 μ...				US Patent US10106527 (2018) BindingDB Entry DOI: 10.7270/Q2PN97Q3
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM293619 (US10106527, Compound 391 | US10544128, Compound 39...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1nncs1 Show InChI InChI=1S/C22H21N7OS/c1-28-6-8-29(9-7-28)20-12-15(4-5-23-20)21(30)26-19-11-18-10-16(22-27-25-14-31-22)2-3-17(18)13-24-19/h2-5,10-14H,6-9H2,1H3,(H,24,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The DYRKIA kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies-a Divis...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM293619 (US10106527, Compound 391 | US10544128, Compound 39...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1nncs1 Show InChI InChI=1S/C22H21N7OS/c1-28-6-8-29(9-7-28)20-12-15(4-5-23-20)21(30)26-19-11-18-10-16(22-27-25-14-31-22)2-3-17(18)13-24-19/h2-5,10-14H,6-9H2,1H3,(H,24,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1QR6
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM293619 (US10106527, Compound 391 | US10544128, Compound 39...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1nncs1 Show InChI InChI=1S/C22H21N7OS/c1-28-6-8-29(9-7-28)20-12-15(4-5-23-20)21(30)26-19-11-18-10-16(22-27-25-14-31-22)2-3-17(18)13-24-19/h2-5,10-14H,6-9H2,1H3,(H,24,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
TBA					Assay Description The DYRKIA kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				Citation and Details BindingDB Entry DOI: 10.7270/Q2JW8JR2
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM293619 (US10106527, Compound 391 | US10544128, Compound 39...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1nncs1 Show InChI InChI=1S/C22H21N7OS/c1-28-6-8-29(9-7-28)20-12-15(4-5-23-20)21(30)26-19-11-18-10-16(22-27-25-14-31-22)2-3-17(18)13-24-19/h2-5,10-14H,6-9H2,1H3,(H,24,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRKIA kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair